Indiana University Integrative Data Science Lab (IDSL)
Welcome to the Integrative Data Science Lab (IDSL) in the School of Informatics and Computing at Indiana University. Integrative Data Science brings together heterogeneous datasets and expertise from different disciplines along with novel data science tools and technologies to solve real world problems. Current research focus areas include Precision Drug Intervention and Smart Communities, Health and Emergency Response. The IDSL is directed by David Wild.
Integrative Data Science for Precision Drug INTERVENTION
A major focus of modern medicine is understanding the molecular bases of disease states and their relationship to particular patient groups and external conditions. Using deep expertise in cheminformatics, biomedical informatics, data linking and heterogeneous graph mining of molecular and patient-level data, we are building tools and methods that identify opportunities to use new chemical entities and to repurpose existing drugs as precision medical interventions. Current projects include identifying repurposing candidates for rare and neglected diseases, using new datasets including gene expression data for repurposing, and creation of targeted interventions by new chemical entities using automated synthesis laboratories. We are thankful to NIH NCATS, Indiana CTSI, the OpenPHACTS foundation, Eli Lilly, and Pfizer for funding of this work.
Integrative Data Science for Smart COMMUNITIES, Health and Emergency Response
We are researching the intersection of data science, smart communities, human computer interaction and heterogeneous data sources to bring tools and actionable data to healthcare, emergency responders, and citizens to enable efficient, informed and cost-effective decision making. Current projects include a partnership with Bloomington City Fire Department in Indiana for data driven situational awareness tools and historical call data mining, and a citywide analysis of drug prescribing and adverse drug interactions in a large city in Brazil.